Physical Education
Ladan Hosseini Abrishami; Seyed Mahmud Hejazi; Amir Rashid Lamir
Volume 27, Issue 5 , November and December 2020, , Pages 710-718
Abstract
Introduction: Adhesive molecules are cellular markers that identify the process of atherosclerotic plaque formation in the endothelial wall of arteries. The aim was evaluation of changes in E-selectin and P-selectin in men with heart failure after eight weeks of continuous and intermittent aerobic exercise.
Materials ...
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Introduction: Adhesive molecules are cellular markers that identify the process of atherosclerotic plaque formation in the endothelial wall of arteries. The aim was evaluation of changes in E-selectin and P-selectin in men with heart failure after eight weeks of continuous and intermittent aerobic exercise.
Materials and Methods: 42 men with heart failure were selected by sampling method as volunteers and were divided into three equal groups (14 subjects) continuous aerobic, intermittent aerobic exercises and control groups. Continuous training (45-70% of Maximum Heart Rate) and intermittent training (45-80% of MHR with 5-10 minutes rest between each period) were done for 8 weeks (three days a week). Fasting blood samples were taken from all subjects before and after eight weeks of aerobic exercise and adhesion molecules were measured by ELISA method. Data were analyzed by ANCOVA at significance levels of P<0.05.
Results: Comparison of the groups with covariance analysis showed that the levels of E-selectin (P=0.002) and P-selectin (P=0.022) levels was significant in all three groups. The Bonferroni test showed, There was a significant difference between the intermittent and control (P=0.005) and between continuous and control groups (P=0.006) at the level of Eselectin and the intermittent aerobic and control groups (P=0.032) at Pselectin level, However, there was no significant change despite a decrease between the control and continuing aerobic (P=0.083) in Pselecteine. Also, there was no significant difference in the studied variables in both intermittent and continuous aerobic groups.
Conclusion: Aerobic exercise with reducing levels of adhesion molecules may play an important role in the prevention and control of cardiovascular diseases in men with heart failure.
Physical Education
Ladan Hosseini Abrishami; Seyed Mahmud Hejazi; Amir Rashdlamir; Rambod Khajei
Volume 26, Issue 4 , November and December 2019, , Pages 495-504
Abstract
IntroductionEvidence showed that adhesion molecules and inflammatory factors play an important role in the pathogenesis of atherosclerosis.The purpose of this study was to evaluate the effect of eight weeks of continuous and periodic aerobic exercise on the serum level of C-reactive protein and some ...
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IntroductionEvidence showed that adhesion molecules and inflammatory factors play an important role in the pathogenesis of atherosclerosis.The purpose of this study was to evaluate the effect of eight weeks of continuous and periodic aerobic exercise on the serum level of C-reactive protein and some adhesive molecules in men with heart failure. Materials and MethodsIn this study, 42 middle-aged men with heart failure were purposeful and randomly divided into three equal groups(14 subjects): continuous aerobic exercise, periodic aerobic exercise and control groups. Continuous training(45-70% of Maximum Heart Rate) and periodic exercise (45-80% of MHR with 5-10 minutes rest between each period) were done for 8 weeks(three days a week). Before and after exercise, blood samples were taken from three groups, ELISA method was used. Data were analyzed using SPSS (20 version) at a significant level of P≤0.05. ResultsAfter eight weeks of training, the level of C-reactive protein, adhesion molecule -1 and vascular adhesion molecule -1 had a significant decrease in the two training groups(P ≤ 0.05). but no significant difference was observed in the control group. There was a significant difference between the levels of hs-CRP(P = 0.023) and VCAM-1(P = 0.0001) in all three groups, but there was not a significant difference in ICAM-1 level(P = 0.17).ConclusionAerobic exercise by decreasing the levels of hs-CRP and VCAM-1 may play an important role in the prevention and control of cardiovascular disease in men with heart failure.
Physical Education
Rambod Khajei; 1. Amir Hossein Haghighi; mohamad reza hamedinia; amir rashid lamir
Volume 25, Issue 4 , September and October 2018, , Pages 507-517
Abstract
Background: Aerobic exercise is the most popular sport activity in cardiac rehab center for increase aerobic ability and decrease in fat mass of cardiovascular disease , the aim of this study was to investigate the effect of eight weeks aerobic exercise on LXR gene expression and lipid profile in middle ...
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Background: Aerobic exercise is the most popular sport activity in cardiac rehab center for increase aerobic ability and decrease in fat mass of cardiovascular disease , the aim of this study was to investigate the effect of eight weeks aerobic exercise on LXR gene expression and lipid profile in middle aged men after CABG.Materials and Methods: The subjects were 20 CABG middle aged male patient were randomly assigned into two group : control (N=10), and aerobic training (n = 10) groups. Exercise group performed aerobic exercises for 8 weeks with an intensity 60% to 80% of heart rate. 48 hours before exercise and 48 hours after the last training session, all subjects blood samples were taken and plasma and monocyte isolation were performed to measure the indices. Data analysis were performed by using t-test and independent t-test, and non-parametric Mann-Whitney and Wilcoxon tests were performed at a significant level of p≤0.05.Results: Significant increase in expression of LXR gene value and HDL and significant decrease in total cholestrole, apo A and B ratio, LDL,TGS in experimental group compared to the control group compared to the control group has seen.Conclusion: Improvement of lipid profiles levels and enhancing the expression of LXR gene after 8 weeks of aerobic exercises showed that Performing regular aerobic exercises as part of the cardiac rehabilitation can be effective in reducing the incidence of atherosclerosis and preventing recurrence of the patient.
Physiology & Pharmacology
mohsen dehbashi; Amir Rashidlamir
Volume 25, Issue 2 , May and June 2018, , Pages 231-239
Abstract
Introduction:The utilization of steroid derivatives has become a major concern in the sport community; the aim of the present study was the investigation of eight weeks testosterone enanthate (TE) administrationand resistance training (RT) effects on liver enzyme profile in male rats.Materials and Methods:The ...
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Introduction:The utilization of steroid derivatives has become a major concern in the sport community; the aim of the present study was the investigation of eight weeks testosterone enanthate (TE) administrationand resistance training (RT) effects on liver enzyme profile in male rats.Materials and Methods:The thirty five rats (age: 10 weeks, weight: 12 ± 200 g) randomly was divided to five groups (n=7) including: 1) control+placebo, 2) RT + placebo, 3) TE, 4) RT + moderate dose of TE, and 5) RT + high dose of TE. The resistance training was consisted of climbing (5 reps/3 sets) a ladder carrying a load suspended from the tail for 8 weeks. At the end, whole blood samples were obtained from the orbital sinus and serum activity of liver enzymes including AST, GGT, ALT and ALP was measured by spectrophotometry.Findings:AST activity RT+HTE group was significantly higher than C, RT and TE groups. This enzyme also had marked higher activity in RT+MTE group compared with C and RT groups(P
Physical Education
Rambod Khajei; Amir Hossein Haghighi; Mohammad Reza Hamedinia; Amir Rashid Lamir
Volume 24, Issue 1 , March and April 2017, , Pages 79-88
Abstract
Background & Objectives: Cardiac rehabilitation is the most important proceeding to reduce the effects of heart surgery and its effects on cardiovascular disease. Exercise training because of low cost and being attractive can be a motivation for patients with cardiac rehabilitation programs.Exercise ...
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Background & Objectives: Cardiac rehabilitation is the most important proceeding to reduce the effects of heart surgery and its effects on cardiovascular disease. Exercise training because of low cost and being attractive can be a motivation for patients with cardiac rehabilitation programs.Exercise has influence on blood cellular components, especially the number of white blood cells, metabolism, metabolites, peptides and different type of gene expression.The aim of this study was to examine the effect of aerobic training on monocytes gene expression ABCG5 in middle-aged men after heart bypass surgery. Materials & Methods: In this semi-experimental study, 20 middle-aged malepatient who had coronary artery bypass surgery, were subjected to the study and were randomly assigned into two groups: control (N=10) and aerobic training (N = 10) groups. Blood samples were taken from subjects before and after training sessions.Monocytes isolated by centrifugation and m-RNA purified by Real-Time PCR was performed.Data were analyzed by ANOVA with repeated measures (SPSS version 16). Results: Results showed that, as a result of exercise training, there was significant increase in mRNA expression of gene ABCG5 in the experimental group than control group. Conclusion: It seems that exercise training as part of the cardiac rehabilitation in patients undergoing coronary artery bypass grafting can improve the reverse cholesterol transport process in the patients by impressing the expression of genes involved in lipid metabolism.